Evaluation of hard gelatin capsules and hydroxypropyl methylcellulose containing ampicillin

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Evaluation and enhancement of physical stability of semi-solid dispersions containing piroxicam into hard gelatin capsules.

The aim of the study was to investigate the physical stability of the semi-solid dispersions into the hard gelatine capsules prepared with Gelucire 44/14, Labrasol and different additives such as microcrystalline cellulose (MCC), mannitol and lactose (alpha-monohydrate) used for enhancing the stability of the formulations. The master dispersion prepared with only Gelucire 44/14 (20% w/w) and La...

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Hydroxypropyl methylcellulose in drug delivery

Hydroxy propyl methyl cellulose can be used in the development of different drug delivery technology. Nowadays it is a widely used polymer and different viscosity grade of this polymer is available. The hydrophilic and hydrophobic form (both variants) of this polymer is also available. This study includes a review of this polymer on use in different drug delivery system mosty focusing on more r...

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ژورنال

عنوان ژورنال: Química Nova

سال: 2012

ISSN: 0100-4042

DOI: 10.1590/s0100-40422012000200010